Somatic action potentials are sufficient for late-phase LTP-related cell signaling
نویسندگان
چکیده
منابع مشابه
Nitric oxide signaling contributes to late-phase LTP and CREB phosphorylation in the hippocampus.
Long-term potentiation (LTP) in the hippocampus has an early phase (E-LTP) that can be induced by one- or two-train tetanization, lasts approximately 1 hr, and is cAMP-dependent protein kinase (PKA) and protein synthesis independent and a late phase (L-LTP) that can be induced by three- or four-train tetanization, lasts >3 hr, and is reduced by inhibitors of PKA and of protein or RNA synthesis....
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Somatic spiking is known to regulate dendritic signaling and associative synaptic plasticity in many types of large neurons, but it is unclear whether somatic action potentials play similar roles in small neurons. Here we ask whether somatic action potentials can also influence dendritic signaling in an electrically compact neuron, the cerebellar stellate cell (SC). Experiments were conducted i...
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Event-related potentials include not only the short duration evoked potentials (EPs) associated with sensory stimulation or motor response but also longer duration potentials such as the contingent negative variation, for which the eliciting events are more complex. For EPs there seems to be a relationship between the latency of the EP component and the degree of influence by more cognitive psy...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2002
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.062510599